Hospital offers living donor liver transplant
UC San Diego Health is now performing live donor liver transplants.
“Unlike any other internal organ, the liver can regrow,” said said Alan Hemming, MD, professor of surgery at UC San Diego School of Medicine and chief of Transplantation and Hepatobiliary Surgery at UC San Diego Health., who has performed more than 1,000 liver transplants and resections. “Surgeons can remove half of the healthy liver from the donor and transplant it into the recipient. Regeneration of the liver in both the donor and recipient begins immediately, with the liver in both patients returning to 80 percent of its original size within 6 weeks with further growth up to one year.”
UC San Diego Health surgeons are the only team currently performing live donor liver transplantation in San Diego and have performed seven of these procedures in the previous year.
In patients who have a qualifying living donor, transplantation can be scheduled electively at a time that is optimized for the recipient and before the onset of life-threatening complications. Life expectancy for the recipient is 90 percent at one year. Risks to the recipient are similar to those for standard liver transplantation.
“This is a surgery that carries risk for the donor with potential complication rates of approximately 25 percent,” said Hemming. “Patients and families should only make a decision about living donor transplantation after being fully informed of the risks and benefits. The increasing need for liver transplantation, lack of available organs and the high death rate for patients on the waiting list has made living donor transplantation a much needed option despite the recognized risks to the donor.”
Living donor transplant surgery requires the coordination of two transplant teams. During surgery, the donor and the recipient are placed in side-by-side operating rooms. One team removes half of the donor’s liver, typically the right half, which is immediately transplanted into the recipient by the second surgical team.
Donors must be less than 60 years old and in excellent health with liver anatomy that is suitable for donation. A living donor doesn’t have to be a blood relative of the liver recipient but must have a compatible blood type. Recipients needing the organ may have a diagnosis of liver cirrhosis, cancer, primary sclerosing cholangitis, or any other patient who would otherwise be considered for liver transplantation.
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